Gene search result
Gene info
Gene Symbol: Acsl4
Gene in Aging Signature (AS)
Gene Description: acyl-CoA synthetase long-chain family member 4
Ensembl ID: ENSMUSG00000031278
Chromosome: X
Organism: mouse
Gene found in signature
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
|---|---|---|---|---|---|---|
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
| Chambers | mouse | HSC | 2007 | microarray | Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. | 17676974 |
| Norddahl | mouse | HSC | 2011 | microarray | Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. | 21549326 |
| Sun | mouse | HSC | 2014 | bulk | Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. | 24792119 |
| Maryanovich | mouse | HSC | 2019 | bulk | Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. | 29736022 |