First author Organism Tissue Year Title Pubmed ID Platform
First author Organism Tissue Year Title Pubmed ID Platform
Renders mouse HSC 2021 Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1. 33504783 bulk
Chambers mouse HSC 2007 Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. 17676974 microarray
Norddahl mouse HSC 2011 Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. 21549326 microarray
Bersenev mouse HSC 2012 Lnk deficiency partially mitigates hematopoietic stem cell aging. 22812478 microarray
Wahlestedt mouse HSC 2013 An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. 23476050 microarray
Sun mouse HSC 2014 Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. 24792119 bulk
Flach mouse HSC 2014 Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. 25079315 microarray
Kowalczyk mouse HSC 2015 Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. 26430063 sc
Grover mouse HSC 2016 Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. 27009448 sc
Kirschner mouse HSC 2017 Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment. 28538171 sc
Mann mouse HSC 2018 Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. 30540934 sc
Maryanovich mouse HSC 2019 Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. 29736022 bulk