Aging Signature
Info
A list of the genes which comprise the Aging Signature. This list provides the gene symbols, gene annotation, average logFC, standard deviation (SD) and number of studies which a certain gene was found to be differentially expressed in ≥ 4 studies out of 12.
Pyramid
Genes found in aging signature (consistency >= 4)
| Gene symbol | Consistency | Average LogFC | SD |
|---|---|---|---|
| Gene symbol | Consistency | Average LogFC | SD |
| Selp | 12 | 3.04 | 1.42 |
| Nupr1 | 11 | 2.27 | 0.95 |
| Mt1 | 11 | 2.13 | 1.48 |
| Plscr2 | 10 | 2.79 | 1.61 |
| Clec1a | 10 | 1.80 | 0.70 |
| Gstm2 | 9 | 2.26 | 1.25 |
| Enpp5 | 9 | 1.55 | 0.77 |
| Itgb3 | 9 | 1.25 | 0.46 |
| Ptprk | 8 | 1.76 | 0.62 |
| Zg16 | 8 | 3.15 | 1.64 |
| Vwf | 8 | 1.37 | 0.62 |
| Alcam | 8 | 1.59 | 0.47 |
| Klhl4 | 8 | 1.57 | 0.14 |
| Tm4sf1 | 8 | 2.46 | 1.46 |
| Mt2 | 8 | 2.90 | 1.61 |
| Sbspon | 8 | 4.19 | 1.86 |
| Gpr183 | 8 | 2.41 | 1.39 |
| Fhl1 | 8 | 1.19 | 0.41 |
| Pbx3 | 8 | 1.09 | 0.27 |
| Neo1 | 8 | 2.02 | 0.87 |
| Cd38 | 8 | 1.57 | 0.88 |
| Trpc1 | 8 | 2.53 | 0.83 |
| Clca3a1 | 8 | 2.85 | 1.00 |
| Tdrd9 | 7 | 2.97 | 1.48 |
| Wwtr1 | 7 | 2.43 | 1.57 |
| Plek | 7 | 1.27 | 0.46 |
| Tmem47 | 7 | 2.18 | 0.58 |
| Aldh1a1 | 7 | 1.71 | 1.10 |
| Gm10419 | 7 | 1.98 | 1.07 |
| Abca4 | 7 | 1.44 | 0.79 |
| Ebi3 | 7 | -1.03 | 0.54 |
| Dnm3 | 7 | 1.80 | 0.79 |
| Cd37 | 7 | -1.08 | 0.81 |
| Dhrs3 | 7 | 1.22 | 0.57 |
| Clu | 6 | 3.54 | 0.98 |
| Tgm2 | 6 | 1.00 | 0.19 |
| Plscr1 | 6 | 1.10 | 0.22 |
| Rorc | 6 | 1.18 | 0.57 |
| Tacstd2 | 6 | 1.09 | 0.42 |
| Pros1 | 6 | 0.97 | 0.33 |
| Ramp2 | 6 | 2.58 | 0.58 |
| Prcp | 6 | 0.97 | 0.16 |
| Fap | 6 | 2.70 | 0.83 |
| Efna1 | 6 | 1.03 | 0.38 |
| Fhdc1 | 6 | 1.47 | 0.67 |
| Rorb | 6 | 2.49 | 1.31 |
| Sult1a1 | 6 | 2.15 | 0.90 |
| Cd86 | 6 | -1.39 | 0.33 |
| Satb1 | 6 | -1.47 | 0.53 |
| Cpne8 | 6 | 1.50 | 0.56 |
| Gadd45g | 6 | 1.54 | 0.90 |
| Phf11d | 6 | 1.66 | 0.35 |
| Pgr | 6 | 1.84 | 0.65 |
| Tmem215 | 6 | 2.56 | 1.24 |
| Adgrg2 | 6 | 2.01 | 0.86 |
| Osmr | 6 | 4.05 | 2.39 |
| Prtn3 | 6 | 0.97 | 0.22 |
| Matn4 | 6 | 2.78 | 2.97 |
| Ehd3 | 6 | 1.72 | 0.76 |
| Cyp26b1 | 5 | 1.11 | 0.57 |
| Bmpr1a | 5 | 2.21 | 0.32 |
| Muc1 | 5 | 2.69 | 1.26 |
| Trim47 | 5 | 1.01 | 0.30 |
| Procr | 5 | 0.63 | 0.09 |
| Tmem176a | 5 | 0.62 | 0.06 |
| Tc2n | 5 | 2.79 | 0.79 |
| Cd34 | 5 | -0.85 | 0.15 |
| Cytip | 5 | 1.05 | 0.26 |
| B3galt1 | 5 | 1.79 | 0.58 |
| Dsg2 | 5 | 1.87 | 0.43 |
| Ghr | 5 | 1.36 | 0.42 |
| Runx1t1 | 5 | 1.66 | 0.57 |
| Arhgap30 | 5 | -0.92 | 0.30 |
| Vldlr | 5 | 1.42 | 0.39 |
| Rhoj | 5 | 1.22 | 0.30 |
| Stom | 5 | 1.12 | 0.77 |
| Cyb561 | 5 | 2.03 | 0.73 |
| Abat | 5 | 1.66 | 0.69 |
| Mab21l2 | 5 | 4.47 | 3.34 |
| Stxbp4 | 5 | 1.14 | 0.28 |
| Mef2c | 5 | 0.86 | 0.30 |
| Arhgap29 | 5 | 0.98 | 0.21 |
| Sfrp1 | 5 | 1.53 | 0.26 |
| Nrg4 | 5 | 1.51 | 0.45 |
| Lst1 | 5 | -0.93 | 0.28 |
| Lpl | 5 | 1.85 | 0.51 |
| Tmem56 | 5 | 2.14 | 1.13 |
| Aspa | 5 | 2.03 | 0.43 |
| Casp12 | 5 | 1.10 | 0.09 |
| Anxa6 | 5 | -2.05 | 1.44 |
| Tm6sf1 | 5 | -1.02 | 0.29 |
| Perp | 5 | 1.87 | 0.52 |
| Plac8 | 5 | -1.36 | 0.75 |
| Mmp2 | 5 | -2.43 | 1.25 |
| Gipc2 | 5 | 3.77 | 3.24 |
| Lpar6 | 5 | 0.84 | 0.46 |
| Pcdhb16 | 5 | 1.41 | 0.33 |
| Npdc1 | 5 | 0.78 | 0.34 |
| Zswim5 | 5 | 2.41 | 1.84 |
| Cntn1 | 5 | 4.04 | 2.76 |
| Mcm7 | 5 | -1.36 | 0.75 |
| Hnf4a | 5 | -1.40 | 0.16 |
| Nrk | 5 | -1.68 | 0.62 |
| Il15 | 5 | -0.74 | 0.11 |
| Il1rapl2 | 5 | 1.55 | 0.46 |
| Gem | 5 | 1.32 | 0.51 |
| Serpinb6a | 5 | 0.89 | 0.14 |
| Abcb1b | 5 | 0.85 | 0.29 |
| Abcb1a | 5 | 1.39 | 0.37 |
| Tsc22d1 | 5 | 0.27 | 1.94 |
| Thbd | 5 | 1.26 | 0.34 |
| Lamp2 | 5 | 0.94 | 0.54 |
| Cysltr2 | 5 | 1.47 | 0.61 |
| Slamf1 | 5 | 0.92 | 0.14 |
| Rassf4 | 5 | -1.26 | 0.30 |
| Jam2 | 5 | 1.94 | 0.76 |
| Klrb1c | 5 | 1.98 | 0.89 |
| Klrb1b | 5 | 1.34 | 1.16 |
| Rnase6 | 5 | -1.12 | 0.44 |
| Ndrg1 | 5 | 1.04 | 0.32 |
| Dennd5b | 5 | 1.13 | 0.53 |
| Ampd3 | 4 | 1.13 | 0.22 |
| Btg2 | 4 | 0.45 | 1.87 |
| Rdh10 | 4 | 1.20 | 0.24 |
| Oxr1 | 4 | 1.19 | 0.22 |
| Syk | 4 | -0.76 | 0.10 |
| Gstm1 | 4 | 0.69 | 0.11 |
| Zfp36 | 4 | 1.52 | 0.66 |
| Serpinb8 | 4 | 0.98 | 0.33 |
| Pla2g4a | 4 | 0.81 | 0.42 |
| Camk1d | 4 | -1.69 | 0.41 |
| Lgals1 | 4 | -1.86 | 0.66 |
| Rfc2 | 4 | -0.64 | 0.08 |
| Trpc6 | 4 | 0.54 | 0.08 |
| Mgst1 | 4 | -0.95 | 0.30 |
| Dnmt3b | 4 | -1.07 | 0.41 |
| Pclo | 4 | 1.99 | 0.74 |
| Slc6a15 | 4 | 1.36 | 1.23 |
| Antxr2 | 4 | -0.81 | 0.13 |
| Plcl1 | 4 | 1.47 | 0.55 |
| Vmp1 | 4 | 1.03 | 0.21 |
| Rbpjl | 4 | 3.45 | 3.25 |
| Fyb | 4 | 0.88 | 0.25 |
| Lsr | 4 | 1.12 | 0.20 |
| Cd200r4 | 4 | 1.62 | 0.53 |
| Kcnip3 | 4 | 0.87 | 0.39 |
| Gda | 4 | 2.17 | 0.67 |
| Tbc1d8 | 4 | 0.96 | 0.25 |
| Ctss | 4 | -0.67 | 1.28 |
| Phactr1 | 4 | 0.97 | 0.55 |
| Flt3 | 4 | -1.13 | 0.55 |
| Mamdc2 | 4 | -0.81 | 0.21 |
| Nt5c3 | 4 | 0.71 | 0.06 |
| Ldhd | 4 | 1.26 | 0.31 |
| C4b | 4 | 2.28 | 1.43 |
| Cd63 | 4 | 0.45 | 0.05 |
| Meis2 | 4 | 1.78 | 0.34 |
| Ndn | 4 | 0.79 | 0.09 |
| Ocln | 4 | 1.31 | 0.28 |
| Amotl2 | 4 | 1.66 | 0.67 |
| Plscr4 | 4 | 0.76 | 0.15 |
| Hpgds | 4 | 1.40 | 0.29 |
| Cyyr1 | 4 | 1.15 | 0.28 |
| Gabra4 | 4 | 4.03 | 1.04 |
| Cxcl16 | 4 | 0.94 | 0.26 |
| Rab34 | 4 | 1.18 | 0.44 |
| Sema7a | 4 | 0.93 | 0.11 |
| Gpx3 | 4 | 0.94 | 0.60 |
| Lrrn1 | 4 | 2.89 | 1.84 |
| Mlec | 4 | -0.73 | 0.08 |
| Bcl6 | 4 | 1.07 | 0.12 |
| Col4a2 | 4 | -1.00 | 0.24 |
| Mcm5 | 4 | -0.80 | 0.25 |
| Acsl4 | 4 | 0.94 | 0.54 |
| Evc | 4 | 0.87 | 0.23 |
| Mmp14 | 4 | 1.35 | 0.33 |
| Muc13 | 4 | 0.63 | 0.09 |
| Ddr1 | 4 | 1.83 | 0.61 |
| Maf | 4 | 1.91 | 0.74 |
| Plxdc2 | 4 | -1.10 | 0.33 |
| S100a6 | 4 | 1.23 | 0.22 |
| Slc28a2 | 4 | -0.61 | 0.19 |
| Ect2 | 4 | -0.78 | 0.09 |
| Exoc6b | 4 | 0.82 | 0.33 |
| Myo1e | 4 | 1.15 | 0.43 |
| Nckap1 | 4 | 0.97 | 0.19 |
| Mmrn1 | 4 | 0.65 | 0.17 |
| Cavin2 | 4 | 1.69 | 0.57 |
| Ly6e | 4 | 0.51 | 0.08 |
| Il12rb2 | 4 | -1.46 | 0.47 |
| Rgn | 4 | 2.50 | 0.51 |
| Tox | 4 | 1.04 | 0.33 |
| Slc14a1 | 4 | 0.95 | 0.63 |
| Sell | 4 | -1.14 | 1.04 |
| Chrna7 | 4 | 2.52 | 0.97 |
| Clec1b | 4 | 1.44 | 0.71 |
| Ntf3 | 4 | 4.67 | 2.54 |
| Lsp1 | 4 | -0.55 | 0.11 |
| Zfp334 | 4 | 1.33 | 0.37 |
| Cldn12 | 4 | 0.64 | 0.10 |
| Cd9 | 4 | 1.04 | 0.68 |
| Socs2 | 4 | -1.41 | 0.44 |
| Asb4 | 4 | 1.58 | 0.09 |
| Id2 | 4 | 1.33 | 0.17 |
| Tnfsf10 | 4 | 0.75 | 0.15 |
| Mllt3 | 4 | 1.10 | 0.64 |
| Egr1 | 4 | 1.06 | 0.26 |
| Kdr | 4 | 1.61 | 0.31 |
| Jun | 4 | 0.91 | 0.35 |
| Gstm7 | 4 | 0.67 | 0.53 |
| Acpp | 4 | 1.62 | 0.40 |
| Arhgef28 | 4 | 0.95 | 0.13 |
| Anxa2 | 4 | -0.76 | 0.19 |
| Art4 | 4 | 0.91 | 0.37 |
| Pdgfd | 4 | 1.07 | 0.17 |
| Ppp1r16b | 4 | 0.70 | 0.23 |
| Prnp | 4 | 0.84 | 0.11 |
| Csf2rb | 4 | -1.30 | 0.65 |
| Ptger4 | 4 | 1.27 | 0.30 |
| Dhx40 | 4 | 0.93 | 0.28 |