Gene search result

Gene info

Gene Symbol: Aldh1a1 Gene in Aging Signature (AS)
Gene Description: aldehyde dehydrogenase family 1, subfamily A1
Ensembl ID: ENSMUSG00000053279
Chromosome: 19
Organism: mouse

Gene found in signature
First author Organism Tissue Year Platform Title Pubmed ID
First author Organism Tissue Year Platform Title Pubmed ID
Chambers mouse HSC 2007 microarray Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. 17676974
Norddahl mouse HSC 2011 microarray Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. 21549326
Bersenev mouse HSC 2012 microarray Lnk deficiency partially mitigates hematopoietic stem cell aging. 22812478
Wahlestedt mouse HSC 2013 microarray An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. 23476050
Kowalczyk mouse HSC 2015 sc Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. 26430063
Grover mouse HSC 2016 sc Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. 27009448
Mann mouse HSC 2018 sc Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. 30540934