Gene search result
Gene info
Gene Symbol: Aldh1a1
Gene in Aging Signature (AS)
Gene Description: aldehyde dehydrogenase family 1, subfamily A1
Ensembl ID: ENSMUSG00000053279
Chromosome: 19
Organism: mouse
Gene found in signature
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
|---|---|---|---|---|---|---|
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
| Chambers | mouse | HSC | 2007 | microarray | Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. | 17676974 |
| Norddahl | mouse | HSC | 2011 | microarray | Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. | 21549326 |
| Bersenev | mouse | HSC | 2012 | microarray | Lnk deficiency partially mitigates hematopoietic stem cell aging. | 22812478 |
| Wahlestedt | mouse | HSC | 2013 | microarray | An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. | 23476050 |
| Kowalczyk | mouse | HSC | 2015 | sc | Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. | 26430063 |
| Grover | mouse | HSC | 2016 | sc | Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. | 27009448 |
| Mann | mouse | HSC | 2018 | sc | Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. | 30540934 |