Gene search result
Gene info
Gene Symbol: Dnmt1
Gene in Aging Signature (AS)
Gene Description: DNA methyltransferase (cytosine-5) 1
Ensembl ID: ENSMUSG00000004099
Chromosome: 9
Organism: mouse
Gene found in signature
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
|---|---|---|---|---|---|---|
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
| Chambers | mouse | HSC | 2007 | microarray | Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. | 17676974 |
| Norddahl | mouse | HSC | 2011 | microarray | Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. | 21549326 |
| Sun | mouse | HSC | 2014 | bulk | Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. | 24792119 |