Gene search result
Gene info
Gene Symbol: Klhl4
Gene in Aging Signature (AS)
Gene Description:
Ensembl ID: ENSMUSG00000025597
Chromosome: X
Organism: mouse
Gene found in signature
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
|---|---|---|---|---|---|---|
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
| Renders | mouse | HSC | 2021 | bulk | Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1. | 33504783 |
| Norddahl | mouse | HSC | 2011 | microarray | Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. | 21549326 |
| Bersenev | mouse | HSC | 2012 | microarray | Lnk deficiency partially mitigates hematopoietic stem cell aging. | 22812478 |
| Wahlestedt | mouse | HSC | 2013 | microarray | An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. | 23476050 |
| Sun | mouse | HSC | 2014 | bulk | Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. | 24792119 |
| Flach | mouse | HSC | 2014 | microarray | Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. | 25079315 |
| Grover | mouse | HSC | 2016 | sc | Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. | 27009448 |
| Maryanovich | mouse | HSC | 2019 | bulk | Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. | 29736022 |