Gene search result
Gene info
Gene Symbol: Mcm7
Gene in Aging Signature (AS)
Gene Description:
Ensembl ID: ENSMUSG00000029730
Chromosome: 5
Organism: mouse
Gene found in signature
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
|---|---|---|---|---|---|---|
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
| Chambers | mouse | HSC | 2007 | microarray | Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. | 17676974 |
| Norddahl | mouse | HSC | 2011 | microarray | Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. | 21549326 |
| Sun | mouse | HSC | 2014 | bulk | Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. | 24792119 |
| Flach | mouse | HSC | 2014 | microarray | Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. | 25079315 |
| Kowalczyk | mouse | HSC | 2015 | sc | Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. | 26430063 |