Gene search result

Gene info

Gene Symbol: Rorc Gene in Aging Signature (AS)
Gene Description: RAR-related orphan receptor gamma
Ensembl ID: ENSMUSG00000028150
Chromosome: 3
Organism: mouse

Gene found in signature
First author Organism Tissue Year Platform Title Pubmed ID
First author Organism Tissue Year Platform Title Pubmed ID
Norddahl mouse HSC 2011 microarray Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. 21549326
Wahlestedt mouse HSC 2013 microarray An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. 23476050
Sun mouse HSC 2014 bulk Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. 24792119
Kowalczyk mouse HSC 2015 sc Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. 26430063
Mann mouse HSC 2018 sc Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. 30540934
Maryanovich mouse HSC 2019 bulk Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. 29736022