Gene search result
Gene info
Gene Symbol: Syk
Gene in Aging Signature (AS)
Gene Description: spleen tyrosine kinase
Ensembl ID: ENSMUSG00000021457
Chromosome: 13
Organism: mouse
Gene found in signature
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
|---|---|---|---|---|---|---|
| First author | Organism | Tissue | Year | Platform | Title | Pubmed ID |
| Norddahl | mouse | HSC | 2011 | microarray | Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. | 21549326 |
| Wahlestedt | mouse | HSC | 2013 | microarray | An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state. | 23476050 |
| Sun | mouse | HSC | 2014 | bulk | Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. | 24792119 |
| Maryanovich | mouse | HSC | 2019 | bulk | Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. | 29736022 |